Memory loss reversed in mice with Alzheimer's

What's the news: Scientists repair memory loss and synaptic plasticity in mice with Alzheimer's.

Why should we believe it: This news is based on a new study published four days ago by scientists at the Buck Institute. They found that a specific protein, KIBRA, is required for synapses to form memories.

Lower levels of KIBRA in the brain were predictive of the severity of dementia caused by Alzheimer's. Giving mice this protein reversed memory loss and improved synaptic plasticity, even in the presence of high levels of disease-causing tau protein.

Why this is a big deal: We currently have several approved treatments to slow the progression of Alzheimer's, but nothing to reverse the damage done.

The present study points in a new direction. If it translates to humans, this KIBRA mechanism could work in tandem with treatments that reduce toxic proteins in the brain to not only prevent the disease, but to reverse it.

So what's next: KIBRA levels could be a new diagnostic tool for Alzheimer's. Even more excitingly, KIBRA might become a direct treatment. The Buck Institute team continues to work on it. In the meantime, stay tuned to The Longevity Newsletter, because I will update you on the latest brain health news as soon as they come out.