Bodybuilding supplement reduces Alzheimer's plaques (in mice)

Safe and well-tolerated, even after long-term use

Body building supplements are not just for big muscles any more

What's the news: Bodybuilding supplement HMB fixes Alzheimer's symptoms in mice.

Why should we believe it: This news is based on a study published earlier this month by scientists at Rush University Medical Center. They looked at the effects of a bodybuilding supplement, β-hydroxy β-methylbutyrate (HMB), in mice. Results: 

  • HMB reduced mouse Alzheimer's plaques

  • HMB improved mouse memory and learning

  • It also increased "morphological plasticity" in the hippocampus of mice brains

A bit of background: In spite of its intimidating name, HMB is a naturally occurring substance in the human body. It's a bioactive metabolite of leucine, an essential amino acid.

HMB is also available as supplement, and it's widely taken by body builders for muscle growth. As a supplement, it's generally safe and well tolerated, without side effects even after prolonged use.

Why this is a big deal: This is only a mouse study, but if it translates in any way to humans, it could be huge news. Alzheimer's disease is the main cause of dementia. It affects more than 50 million people worldwide, and more than 10% of those over 65. Any natural, safe, and cheap treatment that helps slow or stop Alzheimer's progression would be a breakthrough.

So what specifically can you do now: Again, this is only a study in mice. It will take time to be confirmed or disproved in humans. And as you can imagine, a cheap, non-patentable supplement is hardly a priority for big funding.

If you don't want to wait and want to start supplementing with HMB, the typical dose is 3g per day. If you are looking for a brand recommendation, then according to Consumer Lab, Bulk Supplements generally provides high-quality body building supplements, at a fair price. Here's the HMB from Bulk Supplements.